The design and analysis of control policies in multi-hop wireless networks has mainly focused on throughput and stability as measures of performance. While these metrics are important, the development of analytical techniques to study the delay performance is crucial to provide guarantees on the quality of service, network dimensioning (choice of buffer sizes, capacity of links), etc. However, analyzing the delay of throughput- optimal (queue-length based) scheduling policies in such systems is extremely difficult due to the complex correlations that arise between the arrival, service, and the queue length processes. In this talk, I will describe a novel methodology to establish fundamental lower bound on the expected delay performance of the system. Our analysis is supported by extensive numerical studies to suggest that the lower bound captures the important elements (interference, multiplexing and fading) of a wireless network. For the tandem queue network, where the delay optimal policy is known, the expected delay of the optimal policy numerically coincides with the lower bound. I will also present sharper upper bounds for important scheduling policies such as the Maximum Weighted Matching (MWM) type of scheduling policies.