Consider the problem where an experimenter needs to learn a sparse predictor with limited budget for sampling the candidate variables. The experimenter can either use his budget to screen all $p$ variables from $n$ i.i.d. experiments. Or he can spend part of the budget to pre-screen on mn-m$ experiments using the reduced number of pre-screened variables. We introduce a two-stage pre-screening and prediction approach to this problem that using a method we call Predictive Correlation Screening (PCS) in the first stage followed by OLS prediction in the second stage. Our approach is well suited to small sample sizes and high dimensions. We establish asymptotic bounds for the FWER of PCS and the mean square error of the two-stage predictor.