We introduce an interference channel with oblivious encoders, which models a situation in which the encoders are ignorant of the codebooks of one another. We assume that the decoders are cognizant of the codebooks. We study the capacity region of a two-user Z-interference channel with oblivious encoders, and prove that an optimal strategy of the interfered user is to use random constant composition codes. Further, we establish the result that the capacity region of this channel, in the weak interference regime, is equal to the Han-Kobayashi region of the ordinary Z-Interference channel.