IF MIMO receivers mitigate noise amplification in conventional linear receivers by decoding for integer linear combinations of codewords at each receive antenna and track the optimal maximum likelihood decoding performance with low-complexity detection and decoding. This talk reviews the basic IF MIMO transceiver structure built on off-the-shelf binary codes, presents a few performance enhancements in the receiver structure, and discusses how IF can be applied to practical wireless communication systems. Using a representative implementation based on LTE OFDM systems, extensive link-level performance simulations are carried out, which demonstrate that IF MIMO receivers offer significant gains over conventional linear receivers. Impacts on system operations and specifications are discussed for the adoption of practical IF MIMO transceivers in fifth-generation cellular networks.